研究業績

研究業績
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原著論文

"Continual Hyperoxidation of Erythrocytic Peroxiredoxin 2 in Obstructive Sleep Apnea: A Possible Biomarker of Oxidative Stress"
Masako Ueyama, Shin Koike, Hiroshi Kimura, Yuki Ogasawara
ERJ Open Research 00378-2025 (2025).

原著論文

"Novel fluorometric assay of antiglycation activity based on methylglyoxal-induced protein carbonylation"
Koike S, Saito Y, Ogasawara Y
Antioxidants (Basel) 12, 2030 (2023).

総説

"Methylglyoxal, which is also produced by the oxidation of glycerol, a moisturizing component, produce carbonylated collagen in the skin"
Koike S, Sugiura K, Ogasawara Y
IMARS HIGHLIGHTS 18, 5-8 (2023).

著書

"3-Mercaptopyruvate sulfurtransferase: a review of past and present perspectives"
Yuki Ogasawara
Essential Enzymes for Life (Foundations and Frontiers in Enzymology)1st Ed. eBook, pp.55-65, Academic　Press, Elsevier (2023).

原著論文

"Hyperoxidized Peroxiredoxin 2 Is a Possible Biomarker for the Diagnosis of Obstructive Sleep Apnea"
Koike S, Sudo H, Turudome S, Ueyama M, Tanaka Y, Kimura H, Ishida YI, Ogasawara Y
Antioxidants (Basel) 11, 2486 (2022).

原著論文

"Exposure to Heated Tobacco Products Aerosol Causes Acute Stress Responses in the Lung of Mouse"
Koike S, Sato K, Sawa M, Inaba Y, Hattori K, Nakadate K, Ushiyama A, Ogasawara Y
Antioxidants (Basel) 11, 2329 (2022).

原著論文

"Plasma unconjugated bile acids as novel biomarker for schizophrenia"
Koike S, Miyaji Y, Suzuki K, Miyashita M, Itokawa M, Arai M, Ogasawara Y
Biochem. Biophys. Res. Commun. 634, 70-74 (2022).

原著論文

"Carbonylation of skin collagen induced by reaction with methylglyoxal"
Sugiura K, Koike S, Suzuki T, Ogasawara Y
Biochem. Biophys. Res. Commun. 562, 100-104 (2022).

原著論文

"Alkaline stress inhibits the growth of Staphylococcus epidermidis by inducing TCA cycle-triggered ROS production"
Ohkubo T, Matsumoto Y, Ogasawara Y, Sugita T
Biochem. Biophys. Res. Commun. 588, 104-110 (2022).

原著論文

"Inhibition of Amyloid-β aggregation by p-terphenyls from the mushroom Polyozellus multiplex and their neuroprotective effects"
Nakabayashi S., Ishikura A., Fujihara K, Hirabayashi S., Koike S., Sasaki H, Ogasawara Y. Koyama K, Kinoshita K
Heterocycles 104, 2025-2036 (2022).

原著論文

"Exposure to aerosol extract from heated tobacco products causes a drastic decrease of glutathione and protein carbonylation in human lung epithelial cells"
Nishimoto-Kusunose S, Sawa M, Inaba Y, Ushiyama A, Ishii K, Hattori K, Ogasawara Y
Biochem. Biophys. Res. Commun. 580, 92-99 (2022).

原著論文

"Delftia acidovorans secretes substances that inhibit the growth of Staphylococcus epidermidis through TCA cycle-triggered ROS production"
Ohkubo T, Matsumoto Y, Cho O, Ogasawara Y, Sugita T
PloS one 16, 7, e0253618 (2021).

原著論文

"Accumulation of Carbonyl Proteins in the Brain of Mouse Model for Methylglyoxal Detoxification Deficits"
Koike S, Toriumi K, Kasahara S, Kibune Y, Ishida YI, Dan T, Miyata T, Arai M, Ogasawara Y
Antioxidants (Basel, Switzerland) 10, 4, 574 (2021).

原著論文

"A newly developed aerosol exposure apparatus for heated tobacco products for in vivo experiments can deliver both particles and gas phase with high recovery and depicts the time-dependent variation in nicotine metabolites in mouse urine"
Sawa M, Ushiyama A, Inaba Y, Uchiyama S, Hattori K, Ogasawara Y, Ishii K
Nicotine Tob Res. 23, 12, 2145-2152 (2021).

原著論文

"Carbonylation of skin collagen induced by reaction with methylglyoxal"
Sugiura K*, Koike S*, Suzuki T, Ogasawara Y
Biochem Biophys Res Commun. 562, 100-104 (2021).

原著論文

"Simultaneous Determination of Five Bile Acids as Potential Biomarkers for Alzheimer's Disease in Mouse Brain and Plasma"
Koike S, Miyaji Y, Sano H, Aikawa N, Kai M, Kasahara S, Suzuki T, Nishimoto-Kusunose S, Ogasawara Y
Anal Sci. 37, 8, 1165-1170 (2021).

原著論文

"Effects of osmolality on the expression of brain aquaporins in AQP11-null mice"
Koike S, Tanaka Y, Morishita Y, Ishibashi K
Biochimie. 188, 2-6 (2021).

原著論文

"Combined glyoxalase 1 dysfunction and vitamin B6 deficiency in a schizophrenia model system causes mitochondrial dysfunction in the prefrontal cortex"
Toriumi K, Berto S, Koike S, Usui N, Dan T, Suzuki K, Miyashita M, Horiuchi Y, Yoshikawa A, Asakura M, Nagahama K, Lin HC, Sugaya Y, Watanabe T, Kano M, Ogasawara Y, Miyata T, Itokawa M, Konopka G, Arai M
Redox biology 45, 102057 (2021).

原著論文

"Excessively activated plasminogen in human plasma cleaves VWF multimers and reduces collagen-binding activity"
Togashi K, Suzuki S, Morita S, Ogasawara Y, Imamura Y, Shin Y
J Biochem. 168, 355-363 (2020).

原著論文

"Oxidative Formation of Methylglyoxal in Glycerol Preparations during Storage"
Sugiura K, Koike S, Suzuki T, Ogasawara Y
Biol Pharm Bull. 43, 879-883 (2020).